Luxury Hotels in Panama City
Check prices for these dates
Luxury Hotels in Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Top neighbourhoods in Panama City
Casco Viejo
Panama City's Casco Viejo neighbourhood is known for its bars and offers lots of things to see, such as Metropolitan Cathedral of Panama and Interoceanic Canal Museum.

Bella Vista
Panama City's Bella Vista neighbourhood is known for its cafes and restaurants, and entices visitors with attractions, including Via Espana and Iglesia del Carmen.
El Cangrejo
Panama City's El Cangrejo neighbourhood is known for its restaurants and cafes, and entices visitors with attractions, including Crown Casino and Luxor Towers.
San Francisco
Panama City's San Francisco neighbourhood is known for its restaurants and offers lots of things to see, such as ATLAPA Conventions Center and Multiplaza Pacific Mall.
Punta Paitilla
Panama City's Punta Paitilla neighbourhood is known for its restaurants and live music, and entices visitors with attractions, including Avenida Balboa and Multicentro Panama.
Top landmarks in Panama City

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Keep exploring
Keep exploring
- Top areas for Luxury Hotels
- Theme
- Neighbourhoods
- Landmarks
- Star Rating
- Accommodation Types
- Top Cities in Panama
- Hotels close to nearby airports
- More Hotels
- Panama City Hotels with Parking
- Panama City Casino Hotels
- Panama City Business Hotels
- Panama City Hotels with a Pool
- Panama City Family Hotels
- Panama City Hotels with Free Breakfast
- Panama City Hotels with a Gym
- Panama City Cheap Hotels
- Panama City Resorts & Hotels with Spas
- Panama City Beach Hotels
- Panama City Pet-friendly Hotels
- Casco Viejo Hotels
- Bella Vista Hotels
- El Cangrejo Hotels
- San Francisco Hotels
- Calidonia Hotels
- Punta Paitilla Hotels
- San Felipe Hotels
- Costa del Este Hotels
- Marbella Hotels
- Punta Pacifica Hotels
- Obarrio Hotels
- Amador Hotels
- Campo Alegre Hotels
- Santa Ana Hotels
- Parque Lefevre Hotels
- Bethania Hotels
- El Chorrillo Hotels
- Balboa Hotels
- Juan Diaz Hotels
- Pueblo Nuevo Hotels
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Cinta Costera
- Hotels near Avenida Balboa
- Hotels near Amador Causeway
- Hotels near Via Espana
- Hotels near El Dorado Mall
- Hotels near Fuerte Amador Resort & Marina
- Hotels near Panama Viejo
- Hotels near Miraflores Locks
- Hotels near Calle 50
- Hotels near ATLAPA Conventions Center
- Hotels near Los Pueblos Commercial Center
- Hotels near Iglesia del Carmen
- Hotels near Uruguay Street
- Hotels near Metropolitan Cathedral of Panama
- Hotels near Panama Canal Railway
- Hotels near Amador Convention Center
- Hotels near Estadio Rommel Fernandez
- Hotels near Multicentro Panama
- Hotels in Bocas del Toro
- Hotels in Rio Hato
- Hotels in Bastimentos
- Hotels in Boquete
- Hotels in Veracruz
- Hotels in Colon
- Hotels in El Valle de Anton
- Hotels in Tocumen
- Hotels in David
- Hotels in San Blas Islands
- Hotels in Isla Frangipani
- Hotels in David Sur
- Hotels in Playa Coronado
- Hotels in Santa Catalina
- Hotels in Nueva Gorgona
- Hotels in Boca Chica
- Hotels in Ancon
- Hotels in San Carlos
- Hotels in Taboga
- Hotels in El Chiru
- Riande Urban Hotel
- Sofitel Legend Casco Viejo, Panama City
- Marriott Panama Hotel
- Plaza Paitilla Inn Hotel
- Hotel Ojos del Rio
- Residence Inn by Marriott Panama City
- Hyatt Regency Panama City
- Courtyard by Marriott Panama Multiplaza Mall
- Holiday Inn Panama Distrito Financiero by IHG
- Hilton Panama
- MARINN Tropical Vibes Hotel
- Bristol Panama, a Registry Collection Hotel
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Aloft Panama
- Boutique Apartments Panama
- Hotel La Compania, in the Unbound Collection by Hyatt
- Radisson Hotel Panama Canal
- Marriott Executive Apartments Panama City, Finisterre
- Arcadia Condo Suites
- American Trade Hotel
- Summit Rainforest & Golf Resort
- Best Western Plus Panama Zen Hotel
- The Westin Panama
- Renaissance Panama City Hotel
- Hotel San Felipe
- Torres de Alba Hotel & Suites
- Best Western El Dorado Panama Hotel
- Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
- InterContinental Miramar Panama by IHG
- Hotel Casa Panamá
- Magnolia Inn
- Exe Oriental Panama
- Le Meridien Panama
- Ramada Panama Centro Via Argentina
- Gran Evenia Panama
- Hotel Milan
- MARINN PLACE Financial District
- Hilton Garden Inn Panama City Downtown, Panama
- HOTEL SAN THOMAS INN
- Victoria Hotel and Suites Panama
- Panama House Bed & Breakfast
- Casco View Apartments
- Euro Hotel
- Hotel Mio Panama
- Boutique Apartments Panamá Coco del Mar
- Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
- Hotel Terranova
- Yoo Panamá by Boutique Apartments
- San Francisco by Wynwood House
- Innfiniti Hotel & Suites