Hotels in Southwest Illinois

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Southwest Illinois?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southwest Illinois

Learn more about Southwest Illinois

Southwest Illinois is applauded for its entertainment and live music with such cultural attractions as Popeye Museum and Henry N Barkhausen Cache River Wetlands Center. The city has something for everyone including its sports, restaurants, and sights like DuQuoin State Fairgrounds and Rend Lake.

Southern Illinois which includes a lake or waterhole and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

Can I book a refundable accommodation option in Southwest Illinois?
If you want the flexibility to change your plans to Southwest Illinois, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Southwest Illinois if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 193 holiday homes. In addition, there are 70 apartments and 5 condos.
Why should I book my Southwest Illinois hotel with Hotels.com?
There are plenty of reasons to book your Southwest Illinois travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.